IVF Update


^^^ Haha!! ^^^

I had my second ultrasound on Thursday morning. I got in within 10 minutes, which is amazing! My RE is amazing and his nurse is one of the best, but they definitely don’t focus on getting in a hurry about anything. I waited 2+ hours for my baseline ultrasound last week. EEEK! So you can imagine my shock and awe when I was called back to the ultrasound room in ten minutes. I even brought a book to read and had several phone calls to make during my expected wait.

Ultrasound results: 10 follicles per ovary, ranging from small up to 14mm. My endometrial lining was at 8 and my estradiol levels were at 800. All of these numbers are good. My lining has never been thicker than a 7 and I believe 10 is ideal for implantation. My estradiol levels have also never been this high (I have also never taken this many drugs before) regardless, I am pleased.

I will be talking a lot about estradiol and I was unsure of what it was so here is a quick explanation that I got from News Medical: Estradiol (E2) is a female sex hormone that is the predominant estrogen throughout a female’s reproductive years. This hormone has a significant impact on reproductive and sexual function as well as on other organs, including the bones. Estradiol acts primarily as a growth hormone for the reproductive structures including the lining of the vagina, the fallopian tubes, the endometrium and the cervical glands. The hormone is also required to maintain oocytes (eggs in the ovary) and triggers a series of events that lead to ovulation. In addition, estradiol works in conjunction with progesterone to prepare the womb lining for implantation. Those of us diagnosed with PCOS usually have lower than normal E2 levels. I also read somewhere that levels increase by 200-300 per mature follicle.

Here are what normal estradiol levels look like:

  • Children (Pre-Puberty): < 10 pg/mL
  • Males: < 60 pg/mL
  • Ovulating Women Early Follicular: 30 to 100pg/mL
  • Ovulating Women Late Follicular: 100 to 400pg/mL
  • Ovulating Women Luteal Phase: 60 to 150pg/mL
  • Pregnancy Trimester One: 188 to 2497pg/mL
  • Pregnancy Trimester Two: 1278 to 7192pg/mL
  • Pregnancy Trimester Three: 6137 to 3460pg/mL
  • After Menopause < 18 pg/mL

Source: babymed.com

Medications: (Up until 8/21)
  • Follistim 150IUs at 8am daily
  • Menopur 150IUs at 8pm daily
  • Lupron 0.1mg at 8pm daily
  • Metformin 500mg once daily at dinner
*I was told last night to stop Follistim and go to 75IUs on Menopur and keep everything else the same. Today I start back up on 150IUs of Menopur.

Vitamins: Fish oil (twice a day), B6 (twice a day), Calcium Citrate (twice a day), Vitamin D (prescription), Provella and a Prenatal vitamin

Current symptoms: My ovaries feel like grapefruits. But I am drinking Gatorade and V8 like crazy to prevent Ovarian Hyperstimulation Syndrome (OHSS). I have gained a few pounds, my skin is really dry and itchy and I am having non-stop brain farts. Exhibit A: I was trying to tell Josh to turn on the garbage disposal and I called it the trash, the trash compactor, the thing that chops and then just gave up altogether. Exhibit B: I keep forgetting to take my meds on time (which I am usually super anal about), and Exhibit C: I mixed my Menopur medication all wrong, instead of getting 1CC of water I got 2CCs and mixed that into the powder, so I had to put even more of that stinging biotch into my body. Yes, Menopur hurts folks, the actual needle doesn’t hurt at all, but when you inject the medication it feels like what I believe being stabbed would feel like. And I’m not the only one, I’ve read all about it and the consensus is that it is painful and there is nothing you can do about it. I have an aversion to sticking myself with needles so last night I had Josh put the needle in my leg and then I injected the medication very slowly (for almost a minute or two) and took several little stabs of pain rather than one giant stab. So it didn’t hurt as bad when I had control over the pain. The silver lining is that it only hurts for a few seconds.

Mental state: Besides the brain farts, all is well. I actually think the brain farts keep me from stressing. In the past I would usually obsess over giving myself the meds and count down the seconds to when Mary Kathryn would call with estradiol levels and further instructions. Yesterday she didn’t call until 5:30 or so and I totally forgot she was even supposed to call me. I hate taking showers and not being able to exercise but I am walking a lot. Josh walks the dogs with me since I can’t pick them up should I have to for any reason. Life has pretty much revolved around getting the right meds administered at the right time at the right dosage. I am so glad I don’t have to do an 8am shot anymore! I have also been focusing on getting a lot of sleep. The days keep flying by, I haven’t even had time to get bored, be eager or even meditate or pray like I should be. Luckily I took the day off today to relax and catch up on things. Josh’s best friend is getting married tomorrow afternoon so we have the rehearsal dinner to attend tonight and it will pretty much take up the whole day tomorrow (which is totally fine, I love weddings). I also have my next appointment tomorrow morning at 9am to see how my little follies are doing! Hopefully I will have some time to keep updating you all. So far, retrieval is still set for next Wednesday the 27th! I am terrified but excited all at the same time!

Best wishes,




5 thoughts on “IVF Update

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